Publications

Cardiovascular

23 November 2019 Troponin level, age and mortality risk in an unselected population of over 250000 patients – TROP-RISK study. An overview of the study can be found on the Imperial College London website; the full paper can be found on the BMJ website.

26 March 2020 Prognostic significance of troponin level in 3121 patients presenting with atrial fibrillation (The NIHR Health Informatics Collaborative TROP-AF study)’ is available on the JAHA website.

27 August 2020 Invasive versus non-invasive management of elderly patients with non-ST elevation myocardial infarction (SENIOR-NSTEMI): a cohort study based on routine clinical data is available on The Lancet website. An overview of the paper titled Age no criterion for decisions on heart attack treatment ‘ can be found on the Imperial College London website.

22 February 2022 Mortality risk prediction of high-sensitivity C-reactive protein in suspected acute coronary syndrome: A cohort study can be found in PLOS Medicine.

09 March 2022 Prognostic Significance of Ventricular Arrhythmias in 13 444 Patients With Acute Coronary Syndrome: A Retrospective Cohort Study Based on Routine Clinical Data (NIHR Health Informatics Collaborative VA‐ACS Study) can be found in the Journal of the American Heart Association.

26 April 2022 Implications of elevated troponin on time-to-surgery in non-ST elevation myocardial infarction (NIHR Health Informatics Collaborative: TROP-CABG study) is available in the International Journal of Cardiology.

06 June 2022 Prognostic significance of troponin in patients with malignancy (nihr health informatics collaborative trop-malignancy study) is available in BMJ Heart.

06 June 2022 Association between age, troponin level and mortality in patients presenting to hospital with acute pulmonary embolism (nihr health informatics collaborative trop-pe study) is available in BMJ Heart.

06 June 2022 Association between troponin and mortality in acute stroke (nihr health informatics collaborative trop-stroke study) is available in BMJ Heart.

22 December 2022 Developing informatics infrastructure to curate datasets using electronic health record data from five hospitals for translational cardiovascular research is available in the European Health Journal – Digital Health.

02 June 2023 Elevated troponin during hospital admission with infection associated with increased short and long-term mortality is available in BMJ Heart.

06 November 2023The Relationship Between Cardiac Troponin in People Hospitalised for Exacerbation of COPD and Major Adverse Cardiac Events (MACE) and COPD Readmissions is available in the International Journal of Chronic Obstructive Pulmonary Disease.

21 May 2024 Changes in the investigation and management of suspected myocardial infarction and injury during COVID-19: a multi-centre study using routinely collected healthcare data is available on the Frontiers in Cardiovascular Medicine website.

Colorectal Cancer

14 July 2022 Establishing a colorectal cancer research database from routinely collected health data: the process and potential from a pilot study is available at BMJ Health and Care Informatics.

Critical Care

21 December 2017 Critical care data processing tools available on the JOSS website.

01 January 2018 Electronic Health Record Research in Critical Care: The End of the Randomized Controlled Trial? This paper can be found in the Annual Update in Intensive Care and Emergency Medicine 2018.

31 January 2018 Critical Care Health Informatics Collaborative (CCHIC): Data, tools and methods for reproducible research: A multi-centre UK intensive care database available in the International Journal of Medical Informatics.

14 November 2018 Optimal intensive care outcome prediction over time using machine learning available on the PLoS ONE website.

12 September 2019 The Association between Supraphysiologic Arterial Oxygen Levels and Mortality in Critically Ill Patients. A Multicenter Observational Cohort Study available on the American Journal of Respiratory and Critical Care Medicine website.

01 July 2021 Descriptors of Sepsis Using the Sepsis-3 Criteria – A Cohort Study in Critical Care Units Within the U.K. National Institute for Health Research Critical Care Health Informatics Collaborative available on the Critical Care Medicine.

Infectious Diseases

20 November 2019 Evaluating a digital sepsis alert in a London multisite hospital network: a natural experiment using electronic health record data available on the JAMIA website.

Renal Disease

01 February 2018 Long‐ and short‐term outcomes in renal allografts with deceased donors: A large recipient and donor genome‐wide association study available in the American Journal of Transplantation.

22 July 2022 Incidence, Risk Factors, and Effect on Allograft Survival of Glomerulonephritis Post-transplantation in a United Kingdom Population: Cohort Study available at Frontiers in Nephrology.

Viral Hepatitis

25 June 2019 Electronic Health Informatics Data To Describe Clearance Dynamics of Hepatitis B Surface Antigen (HBsAg) and e Antigen (HBeAg) in Chronic Hepatitis B Virus Infection available on the American Society for Microbiology (MBio) website.

14 October 2020 Bimodal distribution and set point HBV DNA viral loads in chronic infection: retrospective analysis of cohorts from the UK and South Africa available on Wellcome Open Research.

19 November 2020 National Institute for Health Research Health Informatics Collaborative: development of a pipeline to collate electronic clinical data for viral hepatitis research. An overview of the paper can be found on the NIHR Oxford BRC website; full paper can be found on the BMJ Health and Care Informatics website.

30 April 2021 Longitudinal Analysis of the Utility of Liver Biochemistry as Prognostic Markers in Hospitalized Patients With Corona Virus Disease 2019 available at Hepatology Communications.

26 June 2021 Hepatitis B virus (HBV) viral load, liver and renal function in adults treated with tenofovir disoproxil fumarate (TDF) vs. untreated: a retrospective longitudinal UK cohort study available at BMC Infectious Diseases. 

11 February 2022 Impact of the COVID-19 pandemic on routine surveillance for adults with chronic hepatitis B virus (HBV) infection in the UK available at Wellcome Open Research. 

16 June 2022 Cohort Profile: National Institute for Health Research Health Informatics Collaborative: Hepatitis B Virus (NIHR HIC HBV) Research Dataset available at International Journal of Epidemiology (IJE)

11 July 2023 Patient Biochemistry and Treatment Need in Chronic Hepatitis B Virus Infection Across Three Continents: Retrospective Cross-Sectional Cohort Studies available at Infectious Diseases and Therapy