Themes

The development of the NIHR HIC capability has focused on key therapeutic areas, chosen for their importance to patients and the NHS and also for the different challenges that they present in terms of data quality and availability:

  • cardiovascular medicine (formerly acute coronary syndromes)
  • critical care
  • ovarian cancer
  • renal transplantation
  • viral hepatitis
  • cancer: breast, colorectal, lung, and prostate
  • infectious diseases
  • hearing loss

In addressing data quality and availability in these areas, the NIHR HIC partners have been able to build upon work by the following organisations:

  • Hepatitis C Virus Research UK (HCV UK)
  • NHS Blood and Transplant (NHSBT)
  • Intensive Care National Audit and Research Centre (ICNARC)
  • Myocardial Ischaemia National Audit Project (MINAP)
  • National Cancer Intelligence Network (NCIN)
  • UK Research Reserve (UKRR)
  • Bloomsbury institute of Intensive Care Medicine (BiICM).

In each theme, clinicians, scientists, and informaticians from the partner organisations work together to deliver the NIHR HIC capability – the data flows and the governance framework – and to demonstrate that capability through exemplar research studies.

Each of the themes is led by a different university-hospital partnership:

  • cardiovascular medicine (formerly acute coronary syndromes), by Imperial College Healthcare NHS Trust and Imperial College London
  • critical care, by University College London Hospitals NHS Foundation Trust and University College London
  • ovarian cancer, by Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge
  • renal transplantation, by Guy’s and St Thomas’ NHS Foundation Trust and King’s College London
  • viral hepatitis, by Oxford University Hospitals NHS Foundation Trust and the University of Oxford
  • breast cancer, by Guy’s and St Thomas’ NHS Foundation Trust and King’s College London
  • colorectal cancer, by Oxford University Hospitals NHS Foundation Trust and the University of Oxford
  • lung cancer, by Imperial College Healthcare NHS Trust and Imperial College London, and University College London Hospitals NHS Foundation Trust and University College London
  • prostate cancer, by University College London Hospitals NHS Foundation Trust and University College London and Guy’s and St Thomas’ NHS Foundation Trust and King’s College London
  • infectious diseases, by Imperial College Healthcare NHS Trust and Imperial College London, and Guy’s and St Thomas’ NHS Foundation Trust and King’s College London
  • hearing loss, by University College London Hospitals NHS Foundation Trust, Nottingham University Hospitals NHS Trust, Manchester University Hospitals NHS Foundation Trust.